Hello,
Every week I meet with physicians, nurse practitioners, and physician assistants from the Cellular Medicine Association for our Journal Club with Pearls & Marketing. We go over new research, answer members’ clinical questions, and share what’s working in practice. Every session is recorded, and the edited transcripts are posted on the membership site, going back to 2018.
Below are some of the sessions on men’s sexual health that I’ve opened to everyone: Peyronie’s disease, erectile dysfunction, the Priapus Toxin™ procedure, penile rehabilitation after prostate surgery, and premature ejaculation. Members get every session, live, each week. If you’d like to join us, here’s how to train as a Priapus Shot® (P-Shot®) provider. — Charles Runels, MD
Contents
- Peyronie’s Disease
- Erectile Dysfunction, the P-Shot® & Research
- Priapus Toxin™ (Botulinum Toxin for ED)
- Penile Rehabilitation & Prostate Surgery
- Premature Ejaculation
- Size, Lichen Sclerosus (BXO) & More
Peyronie’s Disease
- Why the P-Shot® Is Likely the Best First-Line Treatment for Peyronie’s Disease (2026): Xiaflex fracture risk, 15 years of data on Peyronie’s surgery and new-onset ED, and why PRP needs time to grow tissue.
- Peyronie’s After Penile Injections, and Trimix (2026): the TriNetX study, Ronald Virag on PRP versus Xiaflex, and whether a P-Shot® should be standard of care with Trimix.
- “Showers vs. Growers,” Penile Fracture After Xiaflex (2026): penile proportion, the tunica albuginea and the pump, plus a counter-argument paper on PRP for ED.
- Xiaflex Disappears from the World Market? (2025): plus a mathematical model of male tumescence and a survey of doctors treating ED with regenerative therapies.
- Peyronie’s, Hourglass Deformity, and PRP for ED (2023): PRP for Peyronie’s and ED, and the controversy over placebo-controlled PRP studies.
Erectile Dysfunction, the P-Shot® & Research
- Meta-Analysis Supports the P-Shot® Procedure (2024): improved erection after the P-Shot®, how long to wait after NSAIDs, and whether to withdraw the plunger before injecting the corpus cavernosum.
- PRP for ED: Meta-Analysis, Propaganda, and Why the Protocol Matters (2026): plus PRP and smoking, and the limits of placebo.
- A Review of the Treatment Options for ED (2023): is it ethical to ignore regenerative possibilities and only treat symptoms?
- PRP for Erectile Dysfunction and Variations in PRP (2023).
- P-Shot® vs. Shockwave Therapy (2025): plus male fertility and PRP, and treating TMJ to help sexual dysfunction.
- Shock Wave Plus the P-Shot®: Longer Sex and Stronger Erections (2022): research showing that shock wave improves erection, and that adding the P-Shot® also makes sex last more than twice as long, plus peptides.
- ED Research, Penile Rehabilitation, and Peyronie’s (2021): the P-Shot® research for ED, how to make it less effective (straight from the research), and autologous vs. homologous vs. minimally manipulated.
Priapus Toxin™ (Botulinum Toxin for ED)
- Botox for ED: Mechanism of Action and Safety (LD50) (2022): how botulinum toxin improves erection, how much is too much, and educating patients.
- Botox for ED, and Bicycles Causing Sexual Dysfunction (2022).
- How Botulinum Toxin May Improve Erection (2023): BoNT for fibrosis, pearls for injecting the corpus cavernosum, and what to do when a P-Shot® doesn’t work.
- Priapus Toxin™ for ED and Premature Ejaculation (2023): the P-Shot® with and without Priapus Toxin™, plus lichen sclerosus protocols.
- How Many Units of Neurotoxin for the Penis? (2026): plus new definitions of female sexual dysfunction and nitrous oxide problems.
Penile Rehabilitation & Prostate Surgery
- Penile Rehabilitation After Prostate Surgery (2026): the full post-prostatectomy protocol, adding Priapus Toxin™ and timing it, plus PRP for the testicles.
- Nocturnal Erections, but He Loses It Soon After Starting (2024): what to do, plus sympathetic tone, VO2 max, and erections.
Premature Ejaculation
- Botulinum Toxin for Premature Ejaculation, and a Device to Prolong Intercourse (2024): plus a review of regenerative therapies.
- Premature Ejaculation Treatment (2021): how long is not long enough, and why HA instead of PRF.
- Premature Ejaculation, the P-Shot®, and Chronic Prostatitis (2020).
Size, Lichen Sclerosus (BXO) & More
- John Leonardo, MD on Penile Augmentation (2026): his path to PRP, penile augmentation, and toxins for the penis.
- Increasing Girth by Combining the P-Shot® with HA Fillers (2024): plus injecting the testicles with PRP to increase sperm counts.
- Treating BXO (Lichen Sclerosus in Men), and the Priapus Toxin™ (2024): plus how soon after the P-Shot® to add botulinum toxin.
Want every session, live, each week? The Journal Club comes with your Priapus Shot® provider membership. See the training and apply here, or call 888-920-5311.



